强制性
发表于 2025-3-26 23:40:23
Modulation of Rho GTPases and the Actin Cytoskeleton by YopT of , ,minal cysteine. This cleavage results in release of RhoA from the cell membrane and subsequently in blockage of stress fiber formation. Thus YopT impairs cellular functions associated with cytoskeleton rearrangements.
破裂
发表于 2025-3-27 04:14:29
,Grundbegriffe der Erzählanalyse,g pathways in infected host cells. In contrast, a domain of SptP inactivates RhoGTPases by mimicking the activity of eukaryotic GTPase-activating proteins. The .-host cell interaction provides an excellent example for the use of molecular mimicry by bacterial pathogens.
碎石
发表于 2025-3-27 08:24:16
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FRAX-tool
发表于 2025-3-27 10:04:21
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使饥饿
发表于 2025-3-27 15:29:08
Triggered Phagocytosis by ,: Bacterial Molecular Mimicry of RhoGTPase Activation/Deactivation,lls. Here, we focus on the functional mechanism of three of these toxins: SopE, SopE2, and SptP. All three effector proteins change the GTP/GDP loading state of RhoGTPases by transient interactions. SopE and SopE2 mimic eukaryotic G-nucleotide exchange factors and thereby activate RhoGTPase signalin
弹药
发表于 2025-3-27 20:45:48
Regulation of Phagocytosis by Rho GTPases,de, and eventually present peptides derived from particulate antigens. The phagocytic process comprises several sequential and complex events initiated by the recognition of ligands on the surface of the particles by specific receptors on the surface of the phagocytic cells. Receptor clustering at t
得罪
发表于 2025-3-28 01:18:54
The Immunological Synapse and Rho GTPases,now recognized as pivotal regulators of antigen-specific T cell activation by APCs and immunological synapse formation. This review summarizes recent advances in our understanding of how Rho GTPase-dependent pathways control T lymphocyte motility, polarization and activation.
nephritis
发表于 2025-3-28 03:55:43
Rho GTPases and the Control of the Oxidative Burst in Polymorphonuclear Leukocytes,en species (ROS) that are used to kill bacteria within the phagosome. This chapter describes this multicomponent NADPH oxidase system, one of the first cellular systems shown to be directly regulated by Rac GTPases. We present current models of NADPH oxidase regulation by Rac2 and describe how Rac2
小丑
发表于 2025-3-28 07:13:35
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难理解
发表于 2025-3-28 12:41:53
The Type III Cytotoxins of , and , That Modulate the Actin Cytoskeleton,tudies have addressed the molecular interactions of these toxins with host cell signaling pathways and how toxins modulate cellular physiology. Although each individual toxin has a unique mode of action, general themes have started to emerge between bacterial pathogens. During the course of an infec