痴呆 发表于 2025-3-26 21:12:32
Cryo-Electron Microscopy to Study Bax Pores and MOMP,ystems—outer membrane vesicles (OMVs) and liposomes—to visualize the pores in the membrane by using cryo-electron microscopy (cryo-EM). We have revealed the morphology of the pore, determined the localization of Bax labeled with nanogold and have performed image analysis to help understand the mechanisms of pore formation induced by Bax.跟随 发表于 2025-3-27 05:00:43
Rapid Imaging of BCL-2 Family Interactions in Live Cells Using FLIM-FRET,al data acquisition. We developed an automated optical system with eight parallel detectors for rapid and efficient data collection. Here we describe how to use this system for FLIM-FRET imaging of Bcl-2 family protein interactions in a 384-well plate format.AV-node 发表于 2025-3-27 09:02:03
http://reply.papertrans.cn/19/1801/180077/180077_33.png表状态 发表于 2025-3-27 13:31:51
http://reply.papertrans.cn/19/1801/180077/180077_34.pngMAG 发表于 2025-3-27 14:27:31
http://reply.papertrans.cn/19/1801/180077/180077_35.pngHeadstrong 发表于 2025-3-27 19:27:51
http://reply.papertrans.cn/19/1801/180077/180077_36.pngamplitude 发表于 2025-3-28 00:27:28
Overview of BCL-2 Family Proteins and Therapeutic Potentials,ein family, both literally and figuratively. BH3 motifs are present in antiapoptotic and proapoptotic BCL-2 homologs, and in a separate group of unrelated BH3-only proteins often appended to the BCL-2 family. BH3-containing helices mediate many of their physical interactions to determine cell deathperitonitis 发表于 2025-3-28 02:14:38
http://reply.papertrans.cn/19/1801/180077/180077_38.png匍匐前进 发表于 2025-3-28 09:08:37
Application of Mito-Priming to Generate BCL-2 Addicted Cells,gement of mitochondrial outer membrane permeabilization or MOMP to initiate cell death. We have developed a new method, called mito-priming, that allows for rapid and synchronous induction of mitochondrial apoptosis in an on-target manner. Mito-priming uses coexpression of pro- and antiapoptotic BclTRACE 发表于 2025-3-28 11:59:00
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