MULTI
发表于 2025-3-23 10:20:12
https://doi.org/10.1007/978-3-319-20544-1Antimicrobial Activity; Asymmetric Synthesis; Catalytic Asymmetric Synthesis; Dual Stereocontrol; Natura
LIMN
发表于 2025-3-23 16:57:22
978-3-319-37034-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
VAN
发表于 2025-3-23 18:47:26
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Carminative
发表于 2025-3-23 23:13:00
2190-5053 natural product analog.Describes the development of a catalyThis thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthe
intuition
发表于 2025-3-24 04:18:52
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讲个故事逗他
发表于 2025-3-24 09:16:45
https://doi.org/10.1007/978-3-662-03368-5 due to the poor reactivity of the Grignard reagent derived from 2-(bromomethyl)-1,3-dioxolane. The designed synthetic route enabled us to increase the ring size to generate the δ-lactone analogue employing Sharpless asymmetric epoxidation and ZrCl.-catalysed intramolecular acetalisation as the key steps.
sacrum
发表于 2025-3-24 13:46:02
Introduction to the Total Synthesis of Lactone-Containing Natural Products Using ZrCl4, greatest source of potential new pharmaceuticals. The discovery and application of new and interesting methodologies of use in total synthesis is vital to the goals of designing shorter, more elegant and ultimately more reliable syntheses of natural products and analogues.
来就得意
发表于 2025-3-24 18:40:53
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Analogy
发表于 2025-3-24 19:33:38
https://doi.org/10.1007/978-3-662-03368-5 β-methyl group would have on the bioactivity of these compounds. The biological testing of these compounds revealed that none of these analogues showed any antifungal activity however, one of the analogues of malyngolide showed promising activity against MRSA with an MIC of 12.5 μg/mL.
慢慢啃
发表于 2025-3-25 02:58:38
M. Ataharul Islam,Abdullah Al-Shihalows for simple modification of the aryl group and, significantly, substrates containing sterically hindered aryl groups gave the highest levels of enantioselectivity and these aryl groups were readily installed by a Pb-mediated arylation of a β-keto allyl ester.