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Repetitive Administration of Hemoglobin Raffimer in Experimental Models and Clinical Applications,ose. Hb-raffimer appears to be free of severe toxicity, as shown in a variety of topload/repeat dose preclinical animal studies. In addition, Hbraffimer does not appear to be immunogenic. Limited information is available on the acute and chronic effects of high volume infusion in animals and on resp小口啜饮 发表于 2025-3-22 12:02:48
Oxygen Gradients In Vivo Seen by a High Oxygen Affinity HB Polymer,how that carriers with oxygen affinity higher than blood would best deliver oxygen to tissues, although good delivery is produced within a large range of affinities. We tested this hypothesis using a solution of either a high oxygen affinity polymer (ZL-HbBv, P50 = 4mmHg) or of sebacoyl crosslinkedfoliage 发表于 2025-3-22 12:56:01
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The Development of a Second-Generation, Designer, Recombinant Hemoglobin, to hemoglobin contained within a red blood cell. Numerous issues have been raised with their experimental use such as pulmonary and systemic vasoactivity, extravasation of hemoglobin, serum enzyme increases, adverse effects on gastrointestinal motility, generation of myocardial lesions, and potentiamyloid 发表于 2025-3-23 01:52:08
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