即席演说 发表于 2025-3-25 03:51:11

http://reply.papertrans.cn/17/1628/162708/162708_21.png

健谈 发表于 2025-3-25 11:03:05

V. Lange,G. Meyer,H. Rau,A. Mewesgested more than 30 years ago (Belikova et al. 1967). Since then, various oligonucleotide derivatives have been created which are capable of damaging nucleic acids and thereby influencing their function (Knorre et al. 1994). However, such oligonucleotide conjugates have not yet been applied as artif

烦扰 发表于 2025-3-25 12:44:38

http://reply.papertrans.cn/17/1628/162708/162708_23.png

Dna262 发表于 2025-3-25 18:43:27

Nucleic Acids and Molecular Biologyhttp://image.papertrans.cn/b/image/162708.jpg

custody 发表于 2025-3-25 22:19:36

P. G. Friedl,G. Schürmann,Ch. Herfarthles. This simplicity appears to be an advantage when artificial RNases are used in design of therapeutics for controlling gene expression or as components of synthetic conjugates. These conjugates are targeted to specific RNA molecules by oligonucleotides, and unwanted interactions of their componen

接触 发表于 2025-3-26 03:53:20

http://reply.papertrans.cn/17/1628/162708/162708_26.png

Crumple 发表于 2025-3-26 05:34:40

http://reply.papertrans.cn/17/1628/162708/162708_27.png

瘙痒 发表于 2025-3-26 11:21:31

http://reply.papertrans.cn/17/1628/162708/162708_28.png

ALERT 发表于 2025-3-26 13:45:34

V. Lange,G. Meyer,H. Rau,A. Mewes footprinting experiments to analyze the structure of protein-nucleic acid complexes. These cleavage reagents have also been tethered to larger molecules such as oligonucleotides, proteins, and intercalating agents, which confer additional specificity. This review will focus on the 1,1O-phenanthroli

社团 发表于 2025-3-26 17:50:50

0933-1891 s. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets o978-3-642-62139-0978-3-642-18510-6Series ISSN 0933-1891 Series E-ISSN 1869-2486
页: 1 2 [3] 4 5 6
查看完整版本: Titlebook: Artificial Nucleases; Marina A. Zenkova Book 2004 Springer-Verlag Berlin Heidelberg 2004 Catalysis.Cleavage.Conjugates.DNA.Enzyme mimics.N