发怨言
发表于 2025-3-26 22:48:21
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Adenoma
发表于 2025-3-27 01:11:44
Clinical studies with anastrozole,sal women but ovarian oestrogen production diminishes with age. In postmenopausal women, oestrogens are synthesised by the aromatisation of androgen precursors in the skin, muscle, adipose and breast tissue, including malignant breast tumours [.]. Oestrogen action is inhibited by blocking the oestro
Finasteride
发表于 2025-3-27 07:46:00
Lessons from the ArKO mouse,t of the . gene). The P450 gene superfamily is a very large one, containing over 3000 members in some 350 families, of which cytochrome P450 arom is the sole member of family 19 (see .). This haem protein is responsible for binding of the C19 androgenic steroid substrate and catalyzing the series of
卵石
发表于 2025-3-27 10:13:17
Possible additional therapeutic uses of aromatase inhibitors,t use of third-generation aromatase inhibitors has had a major therapeutic impact: emerging clinical evidence for some of them shows that they can achieve superior efficacy to tamoxifen, the gold standard of endocrine care for more than two decades.
Encapsulate
发表于 2025-3-27 13:38:49
Rahul Saxena,Mahipal Jadeja,Vikrant Bhatejarce of oestrogen whereas peripheral tissues such as fat, muscle and the tumour itself are more important in postmenopausal patients [.]. In using drugs to block biosynthesis, it is most attractive to employ agents which specifically affect oestrogen production irrespective of site. Mechanistically,
chemoprevention
发表于 2025-3-27 21:16:08
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NAVEN
发表于 2025-3-28 00:25:30
Management and Industrial Engineeringtrone in peripheral tissues. Aromatase, the enzyme responsible for this conversion, is mainly present in adipose tissue, liver, placenta, muscle, skin and brain. Aromatase activity has also been identified in the epithelial and stromal components of the breast. Therefore, local synthesis of oestroge
发生
发表于 2025-3-28 04:06:19
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Mammal
发表于 2025-3-28 09:39:52
2296-6056 eloped and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy..978-3-7643-8692-4978-3-7643-8693-1Series ISSN 2296-6056 Series E-ISSN 2296-6064
唤起
发表于 2025-3-28 13:29:23
Background and development of aromatase inhibitors,rce of oestrogen whereas peripheral tissues such as fat, muscle and the tumour itself are more important in postmenopausal patients [.]. In using drugs to block biosynthesis, it is most attractive to employ agents which specifically affect oestrogen production irrespective of site. Mechanistically,