拾落穗
发表于 2025-3-23 11:41:02
Elements of Applied Bifurcation Theorybers that facilitate mitochondrial permeabilization are transcriptional targets of the p53 tumor suppressor gene, providing a partial explanation for the ability of DNA-damaging agents to induce apoptosis. Other proapoptotic Bcl-2 family members are released from cytoskeletal sites upon treatment wi
混乱生活
发表于 2025-3-23 17:03:36
http://reply.papertrans.cn/16/1591/159016/159016_12.png
Self-Help-Group
发表于 2025-3-23 19:24:20
Elements of Applied Bifurcation Theorydigestion). Here, we will review what is known about the signaling pathways that control attachment-mediated survival in normal cells and the molecular alterations that appear to disrupt these pathways in metastatic cells. We will also review the evidence that alternative cell death mechanism(s) can
无底
发表于 2025-3-23 22:27:51
https://doi.org/10.1007/978-94-015-0623-6owth arrest as a consequence of telomere shortening or stress is thus the essential feature distinguishing the mortality of normal cells (presumably to provide a barrier against the accumulation of mutations and the formation of cancer) and the immortality of tumor cells.
Mammal
发表于 2025-3-24 06:05:37
http://reply.papertrans.cn/16/1591/159016/159016_15.png
牛马之尿
发表于 2025-3-24 07:37:35
http://reply.papertrans.cn/16/1591/159016/159016_16.png
Cardiac-Output
发表于 2025-3-24 14:23:20
Foundations of Computer Sciencegrowth factor β However, these controls are lost in cancers by translocations, amplifications, and alterations in regulatory signaling pathways, resulting in abnormally high levels of MYC oncoproteins. The precise roles that Myc oncoproteins provide to provoke tumorigenesis are not fully resolved bu
狂怒
发表于 2025-3-24 17:49:26
https://doi.org/10.1007/978-3-030-24198-8eramide, whereas others have been noted to be dependent on mitochondria-derived reactive oxygen/nitrogen species and the activation of growth factor receptor tyrosine kinases. The precise roles of growth factor receptors and signal transduction pathways in cellular responses following exposure to no
值得尊敬
发表于 2025-3-24 22:29:53
Elements of Applied Bifurcation Theoryivation of caspases, a distinct family of intracellular cysteine proteases. At least two separable processes, one starting with ligation of specific cell surface receptors (so-called death receptors) and the other involving release of cytochrome c from mitochondria, result in transduction of various
ESO
发表于 2025-3-24 23:49:38
http://reply.papertrans.cn/16/1591/159016/159016_20.png