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Apoptosis Techniques and Protocols978-1-59259-634-8Series ISSN 0893-2336 Series E-ISSN 1940-6045
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Navigation im Begriffsraum der Musikevi-Montalcini, 1949; Oppenheim, 1991). During this process, immature neurons undergo an active process of cell death, probably because they receive insufficient quantities of trophic factors from their target cells. Active cell death implies a molecular program of cellular-self-destruction and is t
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Navigation im Begriffsraum der Musik 1926; Glücksmann, 1951; Kerr et al., 1972). In the nervous system, programmed cell death of sensory and motor neurons occurs in embryonic stages, but also maturation of central and peripheral nervous system is accompanied by extensive deletion of supernumerary neurons. Furthermore, neuronal cell de
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https://doi.org/10.1007/978-3-7643-7746-5in the rodent olfactory epithelium (Mahalik, 1995). In addition, we are interested in correlating cell death in the rodent CNS with the expression of a putative death-related mRNA called RPS (Owens et al., 1991; Owens et al., 1995; Mahalik et al., 1995). In these studies we have used standard Nissl
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Denotatoren für die Plattform RUBATOed to delineate cell death as “apoptotic” are the condensation of nuclear chromatin and the fragmentation of nuclear DNA into oligonucleosomal-sized fragments (multiples of about 180 bp). After the stimulus that initiates cell death, cells undergoing apoptosis typically show few early morphological
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Denotatoren für die Plattform RUBATOn diseases (Thompson, 1995). Apoptosis can be distinguished from the other major form of cell death, necrosis, on the basis of both morphological and biochemical features; these include chromatin condensation with nuclear pyknosis, and cytoplasmic shrinkage (Thompson, 1995). One prominent hallmark o
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