accessory 发表于 2025-3-30 11:07:58
Continuous Infusion of Antisense Phosphorothioate Therapeutics,rone. Unfortunately, most patients relapse from initial remission. Nearly one-fifth of early relapses experience treatment-related deaths. In addition, patients refractory to Ara-C die within months. Hence, new therapeutic agents must be identified capable of enhanced remission rates, diminished tre别炫耀 发表于 2025-3-30 12:31:52
Protein Kinase-A Directed Antisense Therapy of Tumor Growth In Vivo,herapeutic agent. in principle, an antisense oligonucleotide targeted at a gene essential for neoplastic cell growth should interfere with only that gene’s expression, resulting in arrest of cancer cell growth.放逐 发表于 2025-3-30 19:38:19
http://reply.papertrans.cn/16/1587/158677/158677_53.pngaviator 发表于 2025-3-31 00:00:39
Comparative Pharmacokinetics of Antisense Oligonucleotides,enetic disorders because of their ablhty to inhibit expression of a disease-associated gene in a sequence-specific manner. Gene expression is inhibited by hybrid ization of the oligonucleotide to sequences in the gene or the messenger RNA (mRNA) target by Watson-Crick base pairing. The first example潜移默化 发表于 2025-3-31 00:51:30
http://reply.papertrans.cn/16/1587/158677/158677_55.pngaccomplishment 发表于 2025-3-31 08:34:58
https://doi.org/10.1007/978-3-319-33927-6e (.). The principal cause for disassociation of IkB from NFis phosphorylation (.), but it may involve proteolysis of IkB (.) Several autoregulatory loops have been proposed for the involvement of NF-kB in the regulation of the inhibitor IkB. Furthermore, NF-kB has been shown to regulate the transcrdeforestation 发表于 2025-3-31 09:43:54
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