Glucose
发表于 2025-3-30 10:43:41
https://doi.org/10.1007/b115596d DNA backbones can cause immune activation which is concentration-and length-dependent and sequence-independent. However, the different backbones currently under development for antisense applications differ greatly in the degree to which they induce immune effects. As might be expected, neutral ba
邪恶的你
发表于 2025-3-30 12:54:56
https://doi.org/10.1007/b115596 (for recent reviews, see Weiss et al. ., .,.; .). The antisense approach has been particularly useful in characterizing the pharmacological properties and biological functions of receptors for neurotransmitters. This is due to the rapid discovery of the molecular structure of new subtypes of neurot
隐语
发表于 2025-3-30 16:59:33
https://doi.org/10.1007/b115596any cases the stimuli responsible for this change in brain function also activate transcription factors (TF), some of which are of the immediate-early gene (IEG) family. Stimuli of both physiological and pathophysiological significance have been shown to activate the prototypical IEG, c-.. Consequen
chandel
发表于 2025-3-30 23:20:50
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讥笑
发表于 2025-3-31 04:23:26
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Inferior
发表于 2025-3-31 08:04:15
https://doi.org/10.1007/b115596tant tumors. There is an urgent need for therapeutic alternatives aiming at compounds with better tolerability at efficacious doses that are directed at defined, disease-relevant molecular targets. The progress made in understanding the molecular basis of mammalian cell transformation has led to the
Lucubrate
发表于 2025-3-31 09:21:31
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人造
发表于 2025-3-31 13:54:45
Selected Examples of Spectra of Pairs, at viral penetration and uncoating or viral genome replication, and the era of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) has helped regenerate interest in antiviral drug discovery and development (Table 1). Discovery of many of the active antivirals
眼界
发表于 2025-3-31 20:54:53
https://doi.org/10.1007/978-3-642-74477-8ells relative to that of normal tissue for their therapeutic indices. Small-molecule chemotherapeutic agents have narrow therapeutic indices for a variety of reasons. The most global reason is simply that small molecules do not specifically target cancer cells. However, in addition cytotoxic agents
miscreant
发表于 2025-3-31 22:00:20
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