模范 发表于 2025-3-26 23:45:15
Antibiotic Resistance Due to Reduced Uptake pre-antibiotic era. However, a disturbing trend has also been noted in that, within a very short period of time following the introduction of a new antibiotic, resistance to that antibiotic begins to emerge, a factor that is becoming increasingly meaningful as the discovery of new antibiotics wanessundowning 发表于 2025-3-27 01:07:24
http://reply.papertrans.cn/16/1586/158599/158599_32.pngObligatory 发表于 2025-3-27 08:43:34
The Functional Resistance of Bacterial Biofilmsibiotic therapy, and that an alternative drug must be used. In this chapter, we will concern ourselves with the growing number of bacterial infections in which antibiograms of the causative organism show sensitivity to standard antibiotics in readily attainable concentrations, but the infection fail幻影 发表于 2025-3-27 13:24:42
The Importance of β-Lactamases to the Development of New β-Lactamsheir therapeutic use began with the introduction of benzylpenicillin (penicillin G) during World War II (1, 2), and continues with the development of newer cephalosporins and carbapenems for antibioticresistant infections. These agents act by inhibiting bacterial cell wall synthesis, as a result of不理会 发表于 2025-3-27 16:18:44
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Aminoglycosides: Mechanisms of Action and Resistance They are pseudo-polysaccharides containing amino sugars and can therefore be considered polycationic species for the purpose of understanding their biological interactions. Since they are highly positively charged at physiological pH values, they show high binding affi nity for nucleic acids, espec卵石 发表于 2025-3-27 22:36:35
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http://reply.papertrans.cn/16/1586/158599/158599_39.pngchisel 发表于 2025-3-28 11:36:39
Mechanism of Resistance in Metronidazoleaused by various anaerobic and microaerophilic bacteria (Bacteroides, Clostridia, Helicobacter) and parasites (Trichomonas, Giardia, Entamoeba). Other Gram-positive anaerobes (e.g., lactobacilli, propionobacterium acnes, majority of the periodontal pathogens, peptostreptococci) are known to be inher