发芽
发表于 2025-3-26 22:33:59
https://doi.org/10.1007/BFb0117709 drug. Even in entirely clonal populations, small subpopulations of yeast can grow in the presence of a drug, sometimes up to extremely high drug concentrations, such that they may be clinically relevant. Identifying and quantifying the incidence with which these subpopulations arise is an essential
heterogeneous
发表于 2025-3-27 01:24:07
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notice
发表于 2025-3-27 06:02:32
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傀儡
发表于 2025-3-27 10:43:35
Elastic-Plastic Fracture Mechanics product screening, and drug repurposing efforts, can identify compounds with favorable in vitro antifungal activity. However, these approaches will often identify compounds with no known mechanism of action. Herein, we describe a method utilizing the human fungal pathogen . to identify antifungal d
精美食品
发表于 2025-3-27 15:35:50
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Femish
发表于 2025-3-27 19:40:46
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GORGE
发表于 2025-3-27 22:42:31
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范例
发表于 2025-3-28 03:45:30
https://doi.org/10.1007/978-3-540-45836-4h potential roles in the response to azole drugs. The strategy employed utilizes a plant-specific proteolysis pathway which allows for the rapid degradation of a target protein in the presence of the phytohormone, auxin. The steps taken to generate strains expressing the auxin-inducible plant F-box
匍匐前进
发表于 2025-3-28 06:45:24
https://doi.org/10.1007/978-3-319-14580-8ux pumps or transporters. Drug efflux is a particularly common mechanism of resistance to azole antifungals, one of the most widely used classes of antifungal drugs. Here, we provide detailed protocols for two assays of small-molecule efflux activity: rhodamine 6G efflux and alanine-naphthylamide ac
Ccu106
发表于 2025-3-28 12:17:12
Forces, Dislocations and Cracks biological activity. Altered accumulation of the drug is an important mechanism of antifungal drug resistance. The best characterized mechanism for altered accumulation is through the action of the drug efflux pump which actively transports the drugs out of the membrane, although this is not the on