凹槽 发表于 2025-3-30 11:27:08
https://doi.org/10.1007/978-3-642-18500-7antidepressants; brain; depression; depressive disorder; drug; drug development; genomics; kinetics; personaLUT 发表于 2025-3-30 16:19:04
http://reply.papertrans.cn/16/1586/158535/158535_52.pngComplement 发表于 2025-3-30 19:28:47
https://doi.org/10.1007/978-3-662-07024-6re development of antidepressants. However, attempts to describe the influences of drugs on brain and neuronal function have become increasingly complex, and it is now clear that neuronal processes are complex molecular events involving multiple control factors. The brain consists of approximately 1钻孔 发表于 2025-3-31 00:03:47
https://doi.org/10.1007/978-3-662-07024-6f-life and steady-state concentration, and linear versus nonlinear pharmacokinetics. Factors that can affect the pharmacokinetics of a drug include protein binding, cardiac function and hepatic arterial blood flow, hepatic integrity, renal factors, aging, disease, and gender. An understanding of bas