走路左晃右晃
发表于 2025-3-26 21:51:01
Hans Jürgen Matthies,Karl Theodor Reniusansinoids, auristatins, and calicheamicins are currently being employed or pursued in the clinic as the payloads of ADCs. The structures, mechanisms of action, pharmacokinetics, and toxicities of these toxins are reviewed and discussed. The payloads along with the clinically tested ADCs and their therapeutic areas are summarized.
Mobile
发表于 2025-3-27 05:02:43
http://reply.papertrans.cn/16/1585/158481/158481_32.png
女歌星
发表于 2025-3-27 06:04:40
AAPS Advances in the Pharmaceutical Sciences Serieshttp://image.papertrans.cn/a/image/158481.jpg
Cholagogue
发表于 2025-3-27 10:54:44
https://doi.org/10.1007/978-3-319-13081-1antibody; bio-analysis; immunotoxin; linkers; payloads
anaphylaxis
发表于 2025-3-27 17:18:44
978-3-319-37669-1American Association of Pharmaceutical Scientists 2015
happiness
发表于 2025-3-27 19:40:24
,Elemente und Geräte zur Energieübertragung,t of antibody-mediated “magic bullets.” Progress of ADC development correlated closely with the advances of the knowledge and technology in immunology, conjugation chemistry, molecular biology, and cell biology. Results from diverse studies in different scientific disciplines during the past half ce
Conducive
发表于 2025-3-28 01:10:59
http://reply.papertrans.cn/16/1585/158481/158481_37.png
phase-2-enzyme
发表于 2025-3-28 02:09:19
http://reply.papertrans.cn/16/1585/158481/158481_38.png
Brochure
发表于 2025-3-28 08:39:15
http://reply.papertrans.cn/16/1585/158481/158481_39.png
改变
发表于 2025-3-28 11:42:20
Hans Jürgen Matthies,Karl Theodor Reniusg an antibody with small cytotoxic drugs generally either through lysine ε-amino groups to form a lysine-linked ADC or through sulfhydryl groups of reducing interchain cystine. THIOMAB®–drug conjugates (TDCs) are a new subclass of ADCs in which the engineered free cysteine residues at specific sites