黄油没有 发表于 2025-3-23 12:56:21
Introduction To V-Type Enzymesa comparable change in their affinity for the substrate. When such enzymes are in a normal metabolic pathway, changes in the maximum activity can be up to 30-fold. To be included in this category, enzymes must have at least a doubling in .max, so that this allosteric effect can be physiologically or烦扰 发表于 2025-3-23 14:33:36
G Proteinstivate various cellular receptors and protein kinases. A GTPase activating protein (GAP) can increase this hydrolytic step by up to five orders of magnitude. For this feature these enzymes are called .-type enzymes, even though many G proteins also have significant changes in .d for the bound substrPUT 发表于 2025-3-23 18:28:46
Protein Kinases themselves regulated by phosphorylation, as well as by separate regulatory ligands. The effects of phosphorylation and ligand binding may also be synergistic. Many of these protein kinase activation signals are propagated in sequential protein phosphorylation steps, and the total activation can be周兴旺 发表于 2025-3-23 22:43:48
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isms used for changing enzyme acticity. Eight enzymes are used as model systems after extensive study of their mechanisms. Wherever possible, the human form of the enzyme is used to illustrate the regulatory features..978-1-4419-4453-5978-0-387-72891-9defendant 发表于 2025-3-24 13:38:28
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