DOTE 发表于 2025-3-23 12:28:01
Explaining Small Molecule Binding Specificity with Volumetric Representations of Protein Binding Siplanations about mechanisms for achieving specificity. As a result, mechanistic explanations can potentially be extended to a large space of mutations, including the identification of those that may alter overall binding preferences.ATP861 发表于 2025-3-23 17:31:57
Machine Learning-Based Approaches for Protein Conformational Exploration,omings, and their improved variants. We then focus on new machine learning-based strategies that have been a research hot spot for computational biologists in recent years. These strategies either suggest new approaches or enhancements of existing ones.ENACT 发表于 2025-3-23 19:36:52
http://reply.papertrans.cn/16/1532/153175/153175_13.png笨重 发表于 2025-3-23 22:29:58
Frank J. Robertz,Ruben Wickenhäuserions have a stronger correlation with functional changes in the respective proteins compared to the other kinds of mutations. In this review article, we overview various aspects of InDels, including their origin, their detection among protein sequences, and various methods of analyzing their effects.ovation 发表于 2025-3-24 05:38:23
Detection and Analysis of Amino Acid Insertions and Deletions,ions have a stronger correlation with functional changes in the respective proteins compared to the other kinds of mutations. In this review article, we overview various aspects of InDels, including their origin, their detection among protein sequences, and various methods of analyzing their effects.Osteoporosis 发表于 2025-3-24 08:13:13
http://reply.papertrans.cn/16/1532/153175/153175_16.pngdecode 发表于 2025-3-24 12:34:24
Algorithms and Methods in Structural Bioinformatics978-3-031-05914-8Series ISSN 1568-2684 Series E-ISSN 2662-2432汇总 发表于 2025-3-24 17:33:56
http://reply.papertrans.cn/16/1532/153175/153175_18.pngAngiogenesis 发表于 2025-3-24 22:57:51
Frank J. Robertz,Ruben Wickenhäuserprotein that performs vital functions. Hence, investigating and interpreting protein dynamics as well as their structures can provide us with invaluable insights regarding how proteins perform their functions. In this chapter we survey both experimental and . methods used to study protein dynamics a他很灵活 发表于 2025-3-25 00:13:46
Frank J. Robertz,Ruben Wickenhäusery of debilitating diseases. Performing point mutations via mutagenesis experiments on physical proteins to infer the effects of the mutations is time consuming even for a single amino acid substitution, let alone for all possible mutations. Computational approaches are available for generating mutan