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https://doi.org/10.1007/978-3-031-47262-6ding of Lrp at sites 4,5,6 upstream. Switching to the phase On state requires the environmentally regulated Papl co-regulator, which increases the affinity of Lrp for sites 5 and 2. Papl binds specifically to Lrp-. DNA complexes via binding with Lrp as well as contact with DNA sequences within . sit初学者 发表于 2025-3-22 03:33:10
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Introductiongy, held October 17 and 18, 2002, in Richland, Washington. This is the 40th year in which the laboratory has held an interdisciplinary science symposium to address important biological questions. In years past, the unifying theme was environmental sciences. This year we began a new series of symposiConnotation 发表于 2025-3-22 16:47:52
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A Systems Approach to Discovering Signaling and Regulatory Pathways —or, how to digest large interacinterest. By analogy, if we also wish to elucidate the cadre of signaling and regulatory pathways in the cell, an extremely powerful first step is to construct a complete network of protein-protein and transcriptional interactions and then search through this network to identify critical pathways in向下 发表于 2025-3-23 00:37:44
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Conformational Switching in Muscleibe how we modeled the mechanism of Ca activation, the structure of the muscle proteins, and protein complexes (including actin monomers, tropomysin and troponin complexes, and myosin) to examine two different scientific problems: the mechano-chemical energy transduction mechanism, and the control s