Bridle
发表于 2025-3-28 17:27:20
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放肆的我
发表于 2025-3-28 18:51:04
,Importance of familial Parkinson’s disease and parkinsonism to the understanding of nigral degeneraenesis of PD is supported by the demonstration of the high concordance in twins, increased risk among relatives of PD patients in case control and family studies, and the existence of familial PD and parkinsonism based on single gene defects. Recently, several genes have been mapped and/or identifie
种属关系
发表于 2025-3-28 23:14:18
cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in Mal dopamine neurodegeneration and its protection with R-apomorphine. Both MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and R-apomorphine (R-APO) induced alterations in specific patterns of gene expression. MPTP altered the expression of 49 different genes involved in oxidative stress (oxidati
联合
发表于 2025-3-29 04:46:41
,Monitoring neuroprotection and restorative therapies in Parkinson’s disease with PET,ussed. The potential value of PET and SPECT for assessing the efficacy of putative neuroprotective agents in PD is considered and a review of 18F-dopa PET findings in transplantation trials involving implantation of human and procine fetal mesencephalic tissue is presented. It is concluded that func
ANIM
发表于 2025-3-29 10:15:50
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妈妈不开心
发表于 2025-3-29 13:28:25
TV3326, a novel neuroprotective drug with cholinesterase and monoamine oxidase inhibitory activitieMAO)-B inhibitor, rasagiline (N-propargyl-(1R)aminoindan), possessing both cholinesterase (ChE) and MAO-inhibitory activity. In doses of 35-100 µmoles/kg administered orally to rats, it inhibits ChE by 25-40% and antagonises scopolamine-induced impairments in spatial memory. After daily administrati
轻而薄
发表于 2025-3-29 18:05:18
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过多
发表于 2025-3-29 23:40:50
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匍匐前进
发表于 2025-3-30 00:27:45
Neurorescuing effects of the GAPDH ligand CGP 3466B,ng properties. It is metabolized to (-)-desmethyldeprenyl, which seems to be the active principle, and further to (-)-amphetamine and (-)-methamphetamine, which antagonize its rescuing effects. These complications may explain the limited neurorescuing potential of (-)-deprenyl observed clinically.
Unsaturated-Fat
发表于 2025-3-30 08:06:10
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