INCH 发表于 2025-3-28 16:31:25

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本能 发表于 2025-3-28 19:59:21

https://doi.org/10.1007/978-3-211-09422-8, DNA repair, DNA replication, and transcription, and hence these studies nicely combine our mechanistic interest in basic processes with our interest in aging. CS (Group B), WRN, and other age-related disorders (Bloom, Xeroderma pigmentosum Groups B and D) carry mutations in related genes character

TERRA 发表于 2025-3-29 02:54:08

https://doi.org/10.1007/978-3-211-09422-8pt. The α-hOggl protein has nuclear localization and is ubiquitously expressed in human tissues. Both, α-hOggl and β-hOggl, release 8-OxoG and nick DNA at AP sites. Moreover, when they are expressed in a bacterial . mutant strain, they complement the mutator phenotype. The human . gene was localized

Suppository 发表于 2025-3-29 05:49:03

https://doi.org/10.1007/978-3-211-09422-8rganism. The main AP endonuclease of human cells, Apel protein, is a homolog of . exonuclease III. Apel is a robust enzyme for cleaving abasic sites, and it can replace Apnl to control mutagenesis in yeast. We have studied Apel protein in its interaction with DNA and cleavage of abasic sites. These

意外的成功 发表于 2025-3-29 08:42:47

https://doi.org/10.1007/978-3-211-09422-8e of oxygen. In chromatin, DNA-protein cross-links are formed by combination of two radicals, or by radical addition reactions. A number of analytical techniques have been used to identify and quantify a variety of products of DNA. Many pyrimidine and purine lesions have been identified and quantifi

figment 发表于 2025-3-29 15:09:06

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irradicable 发表于 2025-3-29 17:03:12

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rheumatism 发表于 2025-3-29 22:31:15

Problemstellung und Abgrenzung des Themas,epair enzymes thereby inhibiting certain DNA repair proteins. As the flux of O.. is increased, N- and S-nitrosation reactions are suppressed but oxidative chemistry is enhanced. Thus, depending upon the fluxes of each radical either nitrosation or oxidation chemistry may predominate. A fundamental u

Evolve 发表于 2025-3-30 03:17:48

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confide 发表于 2025-3-30 04:42:14

On the Role of Cash in East Asia,ecause of reduced repair, results in point mutations in the p53 gene and allelic loss of the nevoid BCC (Gorlin’s syndrome) gene located on chromosome 9q. Xeroderma pigmentosum appears to be a valid paradigm for the role of DNA repair in BCC in the general population. An extension of these studies l
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查看完整版本: Titlebook: Advances in DNA Damage and Repair; Oxygen Radical Effec Miral Dizdaroglu,Ali Esat Karakaya Book 1999 Springer Science+Business Media New Yo