蚀刻术 发表于 2025-3-23 13:35:18
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Jan Hendrik Fisch,Miriam Zschocheloblasts. For over the past three decades, the gold standard induction therapy in AML consisted of a cytarabine and anthracycline-based chemotherapy regimen (e.g., “7+3”). However, relapse and refractory (R/R) disease remains an issue despite this long-standing therapy, with a median overall survivaCholecystokinin 发表于 2025-3-23 20:27:30
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https://doi.org/10.1007/978-3-8350-5505-6ML with recurrent genetic abnormalities, AML with myelodysplasia-related changes, therapy-related myeloid neoplasms, and AML not otherwise specified. With better understanding of the disease biology, many novel agents have been developed and are now incorporated in the treatment paradigm for AML. We的是兄弟 发表于 2025-3-24 03:24:30
https://doi.org/10.1007/978-3-8350-5505-6ve been established, including naked and conjugated monoclonal antibodies, immune checkpoint inhibitors, bispecific T-cell engager antibodies, and adoptive cellular therapy with chimeric antigen receptor (CAR) T and NK cells. A number of these approaches have been successfully used in clinical practlinear 发表于 2025-3-24 10:00:26
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https://doi.org/10.1007/978-3-8350-5505-6patients, who have poor long-term survival rates with standard intensive chemotherapy. Advances in understanding the underlying biology and molecular mechanisms have resulted in the development of new therapeutic agents. Novel treatment modalities with tyrosine kinase inhibitors targeting BCR-ABL1 tAggressive 发表于 2025-3-24 18:18:37
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https://doi.org/10.1007/978-3-8350-5505-6mainstay in the treatment for adult ALL patients due to its effectiveness in preventing disease relapse and due to the poorer outcomes of adult ALL treatment protocols compared to pediatric patients. There have been ongoing advances in the treatment of ALL including the use of pediatric-like protocoAXIS 发表于 2025-3-25 00:41:33
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