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Introduction: A Phenomenological Approach,uding changes in binding specificity (Siglec-5, -7, -9, -11, -12 and 14); changes in expression pattern (Siglec-1, -5, -6, and -11); gene conversion (.); gene deletion (.) and pseudogenization (.). Human-unique pseudogenes of ., . and . are also polymorphic within human populations, suggesting ongoi